What is pharmacogenomics?

What is pharmacogenomics?

• A. Study of how genetics affects drug response
• B. Study of disease prevention
• C. Study of pharmacokinetics in liver
• D. Study of drug interactions in polypharmacy

Answer: (A)

Pharmacogenomics is the study of how genetic differences influence drug response, including how well a drug works and the risk of adverse effects. It combines pharmacology with genomics to understand why people metabolize, transport, or respond to medications differently, and uses that information to tailor therapy. For example, certain gene variants can slow or speed up drug metabolism or predict immune reactions, affecting dosing decisions or drug choice. The other topics describe disease prevention, organ-specific pharmacokinetics, or drug–drug interactions in polypharmacy, none of which focus on how genetics shapes drug response.

Pharmacogenomics is the study of how genetic differences influence drug response, including how well a drug works and the risk of adverse effects. It combines pharmacology with genomics to understand why people metabolize, transport, or respond to medications differently, and uses that information to tailor therapy. For example, certain gene variants can slow or speed up drug metabolism or predict immune reactions, affecting dosing decisions or drug choice. The other topics describe disease prevention, organ-specific pharmacokinetics, or drug–drug interactions in polypharmacy, none of which focus on how genetics shapes drug response.